1887

Abstract

The protein composition of several members of the animal picornavirus group is remarkably similar. Thus, the enteroviruses polio type 1, Echo 12 and bovine entero VG-5-27 (Maizel & Summers, 1968; Korant, Lonberg-Holm & Halperen, 1970; Johnston & Martin, 1971), the cardioviruses Maus-Elberfeld and encephalomyocarditis (Rueckert, Dunker & Stoltzfus, 1969; A. T. H. Burness, personal communication), the rhinoviruses 1A and HGP (Medappa, McLean & Rueckert, 1971; E. J. Stott & R. Killington, personal communication) and several of the seven immunological types of foot-and-mouth disease virus (Burroughs 1971; P. Talbot, unpublished observations) contain three polypeptides with molecular weights ranging from 37 to 24 × 10 (VP, VP, VP) and a smaller polypeptide with a molecular weight in the range of 7 to 13.5 × 10 (VP). In several instances the molar ratio of the four polypeptides has been determined and, with the exception of rhinovirus 1A (Medappa 1971), the three larger polypeptides are present in equimolar amounts and the smaller polypeptide is present in a half molar amount relative to the others.

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1972-05-01
2024-11-02
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References

  1. Bachrach H. L., Trautman R., Breesf S. S. 1964; Chemical and physical properties of virtually pure foot- and-mouth disease virus. American Journal of Veterinary Research 25:333
    [Google Scholar]
  2. Brown F., Smale C. J. 1970; Demonstration of three specific sites on the surface of foot- and-mouth disease virus by antibody complexing. Journal of General Virology 7:115
    [Google Scholar]
  3. Burness A. T. H., Clothier F. W. 1970; Particle weight and other biophysical properties of encephalo-myocarditis virus. Journal of General Virology 6:381
    [Google Scholar]
  4. Burroughs J. N., Rowlands D. J., Sangar D. V., Talbot P., Brown F. 1971; Further evidence for multiple proteins in the foot- and-mouth disease virus particle. Journal of General Virology 13:73
    [Google Scholar]
  5. Fenwick M. L. 1968; The effect of reaction with formaldehyde on the sedimentation rates of ribonucleic acids. Biochemical Journal 107:851
    [Google Scholar]
  6. Finch J. T., Klug A. 1966; Arrangement of protein sub-units and the distribution of nucleic acid in turnip yellow mosaic virus. 2. Electron microscopic studies. Journal of Molecular Biology 15:344
    [Google Scholar]
  7. Granboulan N., Girard M. 1969; Molecular weight of poliovirus ribonucleic acid. Journal of Virology 4:475
    [Google Scholar]
  8. Hedrick J. L., Smith A. L. 1968; Size and charge isomer separation and estimation of molecular weights of proteins by disc gel electrophoresis. Archives of Biochemistry and Biophysics 126:155
    [Google Scholar]
  9. Johnston M. D., Martin S. J. 1971; Capsid and procapsid proteins of a bovine enterovirus. Journal of General Virology 11:71
    [Google Scholar]
  10. Korant B. D., Lonberg-Holm K. K., Halperen S. 1970; Structural polypeptides of three rhinoviruses. Biochemical and Biophysical Research Communications 41:477
    [Google Scholar]
  11. Liebermann H. T., Gralheer H. 1968; Some physical properties of purified neurotropic foot-and-mouth disease virus. Acta Virologica 12:181
    [Google Scholar]
  12. Liebermann H. T., Schulze P. 1971; Struktur des Maul-und Klauenseuchevirus 1. Mitteilung: Zum Aufbau der Proteinhülle. Archiv für Experimented Veterinärmedizin 25:171
    [Google Scholar]
  13. Maizel J. V., Summers D. F. 1968; Evidence for differences in size and composition of the poliovirus specific polypeptides in infected HeLa cells. Virology 36:48
    [Google Scholar]
  14. Mak T. W., O’callaghan D. J., Kay C. M., Colter J. S. 1971; Studies of the protein sub-unit of pH- inactivated Mengo virus variants. 2. Physicochemical properties. Virology 43:579
    [Google Scholar]
  15. Medappa K. C., Mclean C., Rueckert R. R. 1971; On the structure of rhinovirus 1A. Virology 44:259
    [Google Scholar]
  16. O’callaghan D. J., Mak T. W., Colter J. S. 1970; Studies of the protein sub-unit of pH-inactivated Mengo virus variants. 1. Polypeptide composition. Virology 42:229
    [Google Scholar]
  17. Rueckert R. R., Dunker A. K., Stoltzfus C. M. 1969; The structure of mouse-Elberfeld virus: a model. Proceedings of the National Academy of Sciences of the United States of America 62:912
    [Google Scholar]
  18. Scraba D. G., Kay C. M., Colter J. S. 1967; Physicochemical studies of three variants of Mengo virus and their constituent ribonucleates. Journal of Molecular Biology 26:67
    [Google Scholar]
  19. Strohmaier K. 1972; Determination of molecular parameters of foot- and-mouth disease virus. Proceedings of the 2nd International Congress for Virology 1971 Ed Melnick J. L. Basel: Karger;
    [Google Scholar]
  20. Strohmaier K., Mussgay M. 1959; Density gradient centrifugation with infectious ribonucleic acid of foot- and-mouth disease virus. Science, New York 130:3369
    [Google Scholar]
  21. Tannock G. A., Gibbs A. J., Cooper P. D. 1970; A re-examination of the molecular weight of poliovirus RNA. Biochemical and Biophysical Research Communications 38:294
    [Google Scholar]
  22. Trautman R., Savan M., Breese S. S. 1959; Partition by zone ultracentrifugation of the two complementfixing particles in the foot- and-mouth disease virus system. Journal of the American Chemical Society 81:4040
    [Google Scholar]
  23. Wild T. F., Brown F. 1970; Replication of foot- and-mouth disease virus ribonucleic acid. Journal of General Virology 7:1
    [Google Scholar]
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