The polypeptides of cells which had been infected with adenovirus and pulse labelled with high specific activity [S]-methionine have been examined by polyacrylamide gel electrophoresis followed by autoradiography. Five virus-particle polypeptides and at least five other polypeptides which appeared to be specific for the infected cell could be discerned. One of the latter polypeptides could be detected very early in infection and is shown to be one of the major components of the previously described P antigen. The experiments also show that in the absence of arginine in the tissue culture medium, the infected cells fail to synthesize the arginine-rich core polypeptide.


Article metrics loading...

Loading full text...

Full text loading...


Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error