1887

Abstract

Summary

Various mammalian cells propagated in serum-free and chemically defined media yielded high titres of Venezuelan equine encephalomyelitis virus. Some difference in maximum titres was noted, depending upon the medium employed. Of the two serum-free media tested, lactalbumin hydrolysate medium was more effective than the chemically defined medium in supporting virus growth. The addition of serum to serum-free cultures at the time of virus inoculation had a pronounced effect characterized by a delay followed by a burst of virus replication to very high titres. Thus, the degree of replication of Venezuelan equine encephalomyelitis virus appeared to be influenced by a variety of unknown nutritional factors.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-10-3-231
1971-03-01
2019-11-13
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-10-3-231
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error