1887

Abstract

SUMMARY

Thirty-five strains of arbovirus were tested for replication in mouse embryo cell cultures; twenty-six of these multiplied and were cytopathogenic. Dengue 1 and dengue 2 may have multiplied without cytopathogenicity. Twenty-three of the viruses were also tested for the production of complement-fixing antigen; twenty-two were positive. Similar end-points were attained using standard inoculum doses in both tubes and mice for parallel titrations of selected viruses. A major advantage of mouse embryo cell cultures is their ready accessibility to all arbovirus laboratories.

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/content/journal/jgv/10.1099/0022-1317-10-2-173
1971-02-01
2022-01-25
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