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Volume 4, Issue 11

Prosthetic valve endocarditis due to highly beta-lactam-resistant : a case report Open Access

Abstract

There are limited reports of patients with prosthetic valve infective endocarditis (IE) or recurrent IE due to highly beta-lactam-resistant viridans group streptococci. We present a case in which a patient with native valve IE due to beta-lactam-susceptible developed prosthetic valve IE due to highly beta-lactam-resistant . A 79-year-old man with a history of native aortic valve IE caused by beta-lactam-susceptible 21 months prior to admission and aortic valve replacement was admitted to our hospital with a 2-week history of general malaise and low-grade fever. Transesophageal echocardiography showed a 20 mm vegetation on the prosthetic aortic valve, and emergency cardiovascular surgery was performed on admission day 2. Three sets of blood cultures on admission were positive for highly beta-lactam-resistant . Vancomycin and cefazolin were administered as initial treatment. After the surgery, the patient was given vancomycin and gentamicin for 2 weeks, followed by vancomycin for 4 weeks. He was relapse-free at the 6-month follow-up. For patients with native valve IE due to who have undergone valve replacement more than 1 year earlier, given the possibility of methicillin-resistant as well as resistance to beta-lactams, it may be advisable to start vancomycin as an initial treatment and continue it until the infecting micro-organism has been proven to be susceptible to beta-lactams.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): drug resistance , endocarditis , heart valve prosthesis , Streptococcus oralis , vancomycin and viridans streptococci
© 2022 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License.
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2022-11-03
2024-05-12
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Prosthetic valve endocarditis due to highly beta-lactam-resistant Streptococcus oralis: a case report
Access Microbiology 4, 000437 (2022); https://doi.org/10.1099/acmi.0.000437
/content/journal/acmi/10.1099/acmi.0.000437
/content/journal/acmi/10.1099/acmi.0.000437
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