1887

Abstract

We report the genome sequence of ATCC 21386, a strain which produces the anti-bacterial and anti-virulence polyketide, aurodox. The genome of ATCC 21386 was sequenced using a multiplatform hybrid approach, revealing a linear genome of ~10 Mbp with a G+C content of 71%. The genome sequence revealed 36 putative biosynthetic gene clusters (BGCs), including a large region of 271 Kbp that was rich in biosynthetic capability. The genome sequence is deposited in DDBJ/EMBL/GenBank with the accession number PRJNA602141.

Funding
This study was supported by the:
  • Medical Research Council (Award MR/V011499/1)
    • Principle Award Recipient: AndrewJ Roe
  • Royal Academy of Engineering (Award RCSRF2021\11\15)
    • Principle Award Recipient: PaulA Hoskisson
  • Biotechnology and Biological Sciences Research Council (Award BB/T004126/1)
    • Principle Award Recipient: PaulA Hoskisson
  • Biotechnology and Biological Sciences Research Council (Award BB/T001038/1)
    • Principle Award Recipient: PaulA Hoskisson
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
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2022-05-30
2024-05-06
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