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Volume 3, Issue 11

Invasive fungal infection: A case report Open Access

Abstract

Geotrichosis is a world-wide mycosis caused by species. We report a rare case of an invasive cutaneous infection by in a female patient with undiagnosed diabetes mellitus. The patient presented with right facial swelling not responding to antibiotics and could not recall trauma to the site of the lesion. Histological examination showed fungal hyphae invading salivary glands and bony tissues, and was isolated from the culture of biopsy material. Matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry (MS) confirmed the fungal species. Broth microdilution showed low minimum inhibitory concentrations (MICs) for itraconazole, posaconazole, voriconazole and amphotericin B. Treatment with sequential administration of intravenous amphotericin B with voriconazole followed by itraconazole led to the resolution of the lesion.

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Keyword(s): Geotrichosis , Geotrichum klebahnii , Geotrichum species , Invasive fungal infection and rare fungal infection
© 2021 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. The Microbiology Society waived the open access fees for this article.
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2021-11-30
2024-05-10
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Invasive Geotrichum klebahnii fungal infection: A case report
Access Microbiology 3, 000287 (2021); https://doi.org/10.1099/acmi.0.000287
/content/journal/acmi/10.1099/acmi.0.000287
/content/journal/acmi/10.1099/acmi.0.000287
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