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Volume 3, Issue 9

necrotizing pancreatitis: an unusual pathogen in pancreatic necrosis infection Open Access

Abstract

Pancreatic necrosis infection (PNI) accounts for about 20–40 % of severe acute pancreatitis. PNI caused by anaerobic bacteria is unusual but when they present, is the microorganism most commonly involved. We present a 60-year-old patient with a previous history of SARS-CoV-2, diagnosed with acute pancreatitis. During the hospitalisation he developed bacteraemia. A CT-scan showed pancreatic gas gangrene and a surgical necrosectomy was performed. was isolated in cultures of the pancreatic tissue and collections. The patient’s clinical status improved after surgery and the appropriate medical therapy. He was discharged 76 days after admission. Nowadays, the ‘step-up approach’ is an accepted therapeutic tool in treatment of pancreatic necrosis and peripancreatic fluid collections. However, most authors suggest that infection requires a more aggressive approach due to the high mortality associated to clostridial infection.

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  • Accepted:
  • Published Online:
Keyword(s): acute pancreatitis , clostridial pancreatic necrosis infection , Clostridium perfringens and pancreatic gas gangrene
© 2021 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. The Microbiology Society waived the open access fees for this article.
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2021-09-15
2024-05-02
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Clostridium perfringens necrotizing pancreatitis: an unusual pathogen in pancreatic necrosis infection
Access Microbiology 3, 000261 (2021); https://doi.org/10.1099/acmi.0.000261
/content/journal/acmi/10.1099/acmi.0.000261
/content/journal/acmi/10.1099/acmi.0.000261
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