1887

Abstract

Until an effective vaccine against SARS-CoV-2 is available on a widespread scale, the control of the COVID-19 pandemic is reliant upon effective pandemic control measures. The ability of SARS-CoV-2 to remain viable on surfaces and in aerosols, means indirect contact transmission can occur and there is an opportunity to reduce transmission using effective disinfectants in public and communal spaces. Virusend (TX-10), a novel disinfectant, has been developed as a highly effective disinfectant against a range of microbial agents. Here we investigate the ability of Virusend to inactivate SARS-CoV-2. Using surface and solution inactivation assays, we show that Virusend is able to reduce SARS-CoV-2 viral titre by 4 log p.f.u. ml within 1 min of contact. Ensuring disinfectants are highly effective against SARS-CoV-2 is important in eliminating environmental sources of the virus to control the COVID-19 pandemic.

Funding
This study was supported by the:
  • Ministry of Defence
    • Principle Award Recipient: EdwardI. Patterson
  • Ministry of Defence
    • Principle Award Recipient: GrantL. Hughes
  • Liverpool School of Tropical Medicine (Award Director's Catalyst Fund)
    • Principle Award Recipient: EdwardI. Patterson
  • National Institute for Health Research (Award NIHR2000907)
    • Principle Award Recipient: GrantL. Hughes
  • UKRI (Award 20197)
    • Principle Award Recipient: GrantL. Hughes
  • National Institutes of Health (Award R21AI138074)
    • Principle Award Recipient: GrantL. Hughes
  • Royal Society Wolfson Fellowship (Award RSWF\R1\180013)
    • Principle Award Recipient: GrantL. Hughes
  • Biotechnology and Biological Sciences Research Council (Award V011278/1)
    • Principle Award Recipient: GrantL. Hughes
  • Biotechnology and Biological Sciences Research Council (Award BB/T001240/1)
    • Principle Award Recipient: GrantL. Hughes
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2021-04-26
2021-05-14
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