1887

Abstract

Introduction:

is an enterohepatic species causing bacteraemia in immunocompromised hosts. Only a few cases of recurrent bacteraemia have been reported in Japan and there are no guidelines regarding antimicrobial treatment for infection.

Case presentation:

bacteraemia was observed in a patient receiving platinum-based chemotherapy for lung cancer. To prevent recurrence, the patient received antibiotic therapy with cefepime, amoxicillin and doxycycline for 6 weeks, which is similar to the therapy for bacteraemia. Bacteraemia recurred despite the long-term antibiotic therapy. We hypothesized that the bacteraemia originated from endogenous infection in the intestinal tract due to the long-term damage of the enteric mucosa by platinum-based drugs and performed selective digestive decontamination (SDD) with kanamycin. Bacteraemia did not recur after SDD.

Conclusion:

Our observations indicate that clinicians should be aware of possible recurrent bacteraemia, which could be effectively prevented by SDD with kanamycin.

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2016-09-01
2020-04-04
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