1887

Abstract

Introduction:

Cavernous sinus thrombosis (CST) is a rare manifestation of cerebral venous thrombosis. We herein describe the first case of CST associated with the oral microbes (Dialister pneumosintes, Slackia exigua and Prevotella baroniae).

Case presentation:

An 82‐year‐old previously self‐supported Japanese woman presented with acute onset of impaired consciousness. Computed tomography revealed intracranial haemorrhage complicated with CST. , and were cultivated from two sets of blood cultures and were identified with 16S rRNA sequencing. The patient was successfully discharged after ampicillin–sulbactam treatment, which was performed soon after admission.

Conclusion:

To our knowledge, this is the first description of CST caused by , and . CST should be considered in cases of unusual distribution of cerebral haemorrhage.

Loading

Article metrics loading...

/content/journal/jmmcr/10.1099/jmmcr.0.002683
2014-09-01
2019-10-15
Loading full text...

Full text loading...

/deliver/fulltext/jmmcr/1/3/jmmcr002683.html?itemId=/content/journal/jmmcr/10.1099/jmmcr.0.002683&mimeType=html&fmt=ahah

References

  1. Bahrani‐Mougeot F.K. , Paster B.J. , Coleman S. , Barbuto S. , Brennan M.T. , Noll J. , Kennedy T. , Fox P.C. , Lockhart P.B. . ( 2007; ). Molecular analysis of oral and respiratory bacterial species associated with ventilator‐associated pneumonia. . J Clin Microbiol 45:, 1588–1593.[CrossRef]
    [Google Scholar]
  2. Bakac G. , Wardlaw J.M. . ( 1997; ). Problems in the diagnosis of intracranial venous infarction. . Neuroradiol 39:, 566–570.[CrossRef]
    [Google Scholar]
  3. Booth V. , Downes J. , Van den Berg J. , Wade W.G. . ( 2004; ). Gram‐positive anaerobic bacilli in human periodontal disease. . J Periodontal Res 39:, 213–220.[CrossRef]
    [Google Scholar]
  4. Bukki J. , Huttner H.B. , Lee D.H. , Jantsch J. , Janka R. , Ostgathe C. . ( 2011; ). Polymicrobial feculent meningitis with detection of Slackia exigua in the cerebrospinal fluid of a patient with advanced rectal carcinoma. . J Clin Oncol 29:, e852–e854.[CrossRef]
    [Google Scholar]
  5. Chang C.S. , Liou C.W. , Huang C.C. , Lui C.C. , Chang K.C. . ( 2004; ). Cavernous sinus thrombosis and cerebral infarction caused by Fusobacterium nucleatum infection. . Chang Gung Med J 27:, 459–463.
    [Google Scholar]
  6. Chen H.W. , Su C.P. , Su D.H. , Chen H.W. , Chen Y.C. . ( 2006; ). Septic cavernous sinus thrombosis: an unusual and fatal disease. . J Formos Med Assoc 105:, 203–209.[CrossRef]
    [Google Scholar]
  7. Contreras A. , Doan N. , Chen C. , Rusitanonta T. , Flynn M.J. , Slots J. . ( 2000; ). Importance of Dialister pneumosintes in human periodontitis. . Oral Microbiol Immunol 15:, 269–272.[CrossRef]
    [Google Scholar]
  8. Desa V. , Green R. . ( 2012; ). Cavernous sinus thrombosis: current therapy. . J Oral Maxillofac Surg 70:, 2085–2091.[CrossRef]
    [Google Scholar]
  9. Doan N. , Contreras A. , Flynn J. , Slots J. , Chen C. . ( 2000; ). Molecular identification of Dialister pneumosintes in subgingival plaque of humans. . J Clin Microbiol 38:, 3043–3047.
    [Google Scholar]
  10. Downes J. , Munson M.A. , Spratt D.A. , Kononen E. , Tarkka E. , Jousimies‐Somer H. , Wade W.G. . ( 2001; ). Characterisation of Eubacterium‐like strains isolated from oral infections. . J Med Microbiol 50:, 947–951.
    [Google Scholar]
  11. Downes J. , Sutcliffe I. , Tanner A.C. , Wade W.G. . ( 2005; ). Prevotella marshii sp. nov. and Prevotella baroniae sp. nov., isolated from the human oral cavity. . Int J Syst Evol Microbiol 55:, 1551–1555.[CrossRef]
    [Google Scholar]
  12. Drago L. , Vassena C. , Saibene A.M. , Del Fabbro M. , Felisati G. . ( 2013; ). A case of coinfection in a chronic maxillary sinusitis of odontogenic origin: identification of Dialister pneumosintes . . J Endodont 39:, 1084–1087.[CrossRef]
    [Google Scholar]
  13. Ebright J.R. , Pace M.T. , Niazi A.F. . ( 2001; ). Septic thrombosis of the cavernous sinuses. . Arch Intern Med 161:, 2671–2676.[CrossRef]
    [Google Scholar]
  14. Ferro J.M. , Canhao P. , Stam J. , Bousser M.G. , Barinagarrementeria F. . ( 2004; ). Prognosis of cerebral vein and dural sinus thrombosis: results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT). . Stroke 35:, 664–670.[CrossRef]
    [Google Scholar]
  15. Filippidis A. , Kapsalaki E. , Patramani G. , Fountas K.N. . ( 2009; ). Cerebral venous sinus thrombosis: review of the demographics, pathophysiology, current diagnosis, and treatment. . Neurosurg Focus 27:, E3.[CrossRef]
    [Google Scholar]
  16. Girot M. , Ferro J.M. , Canhao P. , Stam J. , Bousser M.G. , Barinagarrementeria F. . ( 2007; ). Predictors of outcome in patients with cerebral venous thrombosis and intracerebral hemorrhage. . Stroke 38:, 337–342.[CrossRef]
    [Google Scholar]
  17. Kim K.S. , Rowlinson M.C. , Bennion R. , Liu C. , Talan D. , Summanen P. , Finegold S.M. . ( 2010; ). Characterization of Slackia exigua isolated from human wound infections, including abscesses of intestinal origin. . J Clin Microbiol 48:, 1070–1075.[CrossRef]
    [Google Scholar]
  18. Moore L.V. , Moore W.E. . ( 1994; ). Oribaculum catoniae gen. nov., sp. nov.; Catonella morbi gen. nov., sp. nov.; Hallella seregens gen. nov., sp. nov.; Johnsonella ignava gen. nov., sp. nov.; and Dialister pneumosintes gen. nov., comb. nov., nom. rev., anaerobic Gram‐negative bacilli from the human gingival crevice. . Int J Syst Bacteriol 44:, 187–192.[CrossRef]
    [Google Scholar]
  19. Palestro C.J. , Malat J. , Gladstone A.G. , Richman A.H. . ( 1986; ). Gallium scintigraphy in a case of septic cavernous sinus thrombosis. . Clin Nucl Med 11:, 636–639.[CrossRef]
    [Google Scholar]
  20. Rocas I.N. , Alves F.R. , Santos A.L. , Rosado A.S. , Siqueira J.F. Jr . ( 2010; ). Apical root canal microbiota as determined by reverse‐capture checkerboard analysis of cryogenically ground root samples from teeth with apical periodontitis. . J Endodont 36:, 1617–1621.[CrossRef]
    [Google Scholar]
  21. Rousee J.M. , Bermond D. , Piemont Y. , Tournoud C. , Heller R. , Kehrli P. , Harlay M.L. , Monteil H. , Jaulhac B. . ( 2002; ). Dialister pneumosintes associated with human brain abscesses. . J Clin Microbiol 40:, 3871–3873.[CrossRef]
    [Google Scholar]
  22. Sakamoto M. , Rocas I.N. , Siqueira J.F. Jr , Benno Y. . ( 2006; ). Molecular analysis of bacteria in asymptomatic and symptomatic endodontic infections. . Oral Microbiol Immunol 21:, 112–122.[CrossRef]
    [Google Scholar]
  23. Siqueira J.F. Jr , Rocas I.N. . ( 2009; ). The microbiota of acute apical abscesses. . J Dent Res 88:, 61–65.[CrossRef]
    [Google Scholar]
  24. Southwick F.S. , Richardson E.P. , Swartz M.N. . ( 1986; ). Septic thrombosis of the dural venous sinuses. . Medicine 65:, 82–106.[CrossRef]
    [Google Scholar]
  25. Thatai D. , Chandy L. , Dhar K.L. . ( 1992; ). Septic cavernous sinus thrombophlebitis: a review of 35 cases. . J Indian Med Assoc 90:, 290–292.
    [Google Scholar]
  26. Wade W.G. , Downes J. , Dymock D. , Hiom S.J. , Weightman A.J. , Dewhirst F.E. , Paster B.J. , Tzellas N. , Coleman B. . ( 1999; ). The family Coriobacteriaceae: reclassification of Eubacterium exiguum (Poco et al. 1996) and Peptostreptococcus heliotrinreducens (Lanigan 1976) as Slackia exigua gen. nov., comb. nov. and Slackia heliotrinireducens gen. nov., comb. nov., and Eubacterium lentum (Prevot 1938) as Eggerthella lenta gen. nov., comb. nov. . Int J Syst Bacteriol 49:, 595–600.[CrossRef]
    [Google Scholar]
  27. Woo P.C. , Tse H. , Chan K.M. , Lau S.K. , Fung A.M. , Yip K.T. , Tam D.M. , Ng K.H. , Que T.L. , Yuen K.Y. . ( 2004; ). Streptococcus milleri” endocarditis caused by Streptococcus anginosus . . Diagn Microbiol Infect 48:, 81–88.[CrossRef]
    [Google Scholar]
  28. Yarington C.T. Jr . ( 1977; ). Cavernous sinus thrombosis revisited. . Proc R Soc Med 70:, 456–459.
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmmcr/10.1099/jmmcr.0.002683
Loading
/content/journal/jmmcr/10.1099/jmmcr.0.002683
Loading

Data & Media loading...

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error