1887

Abstract

Introduction:

Severe bacterial infection is an unusual initial presentation of systemic lupus erythematosus (SLE).

Case presentation:

We describe two cases of severe encapsulated bacterial infection in women with previously undiagnosed SLE.

Conclusion:

Hypocomplementaemia associated with SLE is an important infection risk and should be considered in the evaluation of patients who present with unusual and severe infection with encapsulated bacteria.

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2014-06-01
2019-10-14
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References

  1. Borenstein D.G. , Simon G.L. . ( 1986; ). Haemophilus influenzae septic arthritis in adults. A report of four cases and a review of the literature. . Medicine 65:, 191–201.[CrossRef]
    [Google Scholar]
  2. Charuvanij S. , Houghton K.M. . ( 2009; ). Acute epiglottitis as the initial presentation of pediatric systemic lupus erythematosus. . Pediatr Rheumatol 7:, 19.[CrossRef]
    [Google Scholar]
  3. Cuchacovich R. , Gedalia A. . ( 2009; ). Pathophysiology and clinical spectrum of infections in systemic lupus erythematosus. . Rheum Dis Clin North Am 35:, 75–93.[CrossRef]
    [Google Scholar]
  4. Hill M.D. , Karsh J. . ( 1997; ). Invasive soft tissue infections with Streptococcus pneumoniae in patients with systemic lupus erythematosus. Case report and review of the literature. . Arthritis Rheum 40:, 1716–1719.[CrossRef]
    [Google Scholar]
  5. Kamran M. , Wachs J. , Putterman C. . ( 2008; ). Necrotizing fasciitis in systemic lupus erythematosus. . Sem Arthritis Rheum 37:, 236–242.[CrossRef]
    [Google Scholar]
  6. Petri M. . ( 1998; ). Infection in systemic lupus erythematosus. . Rheum Dis Clin North Am 24:, 423–456.[CrossRef]
    [Google Scholar]
  7. Petri M. , Orbai A. , Alarcon G.S. , Gordon C. , Merill J.T. , Fortin P.R. , Bruce I.N. , Isenberg D. , Wallace D.J. . other authors ( 2012; ). Derivation and validation of the systemic lupus international collaborating clinics classification criteria for systemic lupus erythematosus. . Arthritis Rheum 68:, 2677–2686.[CrossRef]
    [Google Scholar]
  8. Petros D. , West S. . ( 1998; ). Overwhelming pneumococcal bacteraemia in systemic lupus erythematosus. . Ann Rheum Dis 48:, 333–335.[CrossRef]
    [Google Scholar]
  9. Robinson A.B. , DeWitt E.M. , Schanberg L.E. , Moody A.M. . ( 2010; ). Necrotizing fasciitis caused by Haemophilus influenzae type E in a 17‐year‐old girl with systemic lupus erythematosus. . J Clin Rheumatol 16:, 49–50.[CrossRef]
    [Google Scholar]
  10. Ross S.C. , Densen P. . ( 1984; ). Complement deficiency states and infection: epidemiology, pathogenesis and consequences of neisserial and other infections in an immune deficiency. . Medicine 63:, 243–273.[CrossRef]
    [Google Scholar]
  11. Santilli D. , Govoni M. , Prandini N. , Rizzo N. , Trotta F. . ( 2003; ). Autosplenectomy and antiphospholipid antibodies in systemic lupus erythematosus: a pathogenic relationship?. . Semin Arthritis Rheum 33:, 125–133.[CrossRef]
    [Google Scholar]
  12. Truedsson L. , Bengtsson A.A. , Sturfelt G. . ( 2007; ). Complement deficiency and systemic lupus erythematosus. . Autoimmunity 40:, 560–566.[CrossRef]
    [Google Scholar]
  13. Unsworth D.J. . ( 2008; ). Complement deficiency and disease. . J Clin Pathol 61:, 1013–1017.[CrossRef]
    [Google Scholar]
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