Full text loading...
Abstract
The aim of this study was to determine the extent of EMRSA-15 spread in hospitals in Singapore. Molecular analysis of 197 non-duplicate meticillin-resistant Staphylococcus aureus (MRSA) isolates collected from five acute care public hospitals in Singapore in May 2005 revealed that 66 (33.5 %) were EMRSA-15 while 121 (61.4 %) belonged to the endemic multidrug-resistant ST239 clone. Median and mode vancomycin MIC for both major clones of health-care-associated MRSA were relatively high at 2.0 μg ml−1. Subsequent laboratory surveillance data collected from the first half of 2006 confirmed increasing numbers of the EMRSA-15 clone – ranging from 25.0 to 66.1 % of all MRSA isolated in local hospitals – replacing the ST239 clone island-wide.
- Received:
- Accepted:
- Published Online:
Keyword(s):
HA-MRSA, health-care-associated meticillin-resistant Staphylococcus aureus
,
MLST, multilocus sequence typing
,
MLVA, multilocus variable-number tandem-repeat analysis
,
MRSA, meticillin-resistant Staphylococcus aureus
and
SGH, Singapore General Hospital
SGM