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Volume 71, Issue 8

JMM Profile: Avian paramyxovirus type-1 and Newcastle disease: a highly infectious vaccine-preventable viral disease of poultry with low zoonotic potential Open Access

This article is part of the JMM Profiles collection

Abstract

Newcastle disease (ND) is a highly contagious disease of poultry caused by virulent avian paramyxovirus-1 (APMV-1) (previously termed avian avulavirus-1 and avian orthoavulavirus-1). APMV-1 is endemic in poultry in many developing countries, whilst outbreaks still occur in developed countries, affecting both commercial and backyard flocks. ND outbreaks can have substantial economic consequences due to high mortality rates and the imposition of trade restrictions. APMV-1 nucleic acid can be detected from swabs or tissues of suspected cases by PCR. Evidence of infection or vaccination may be demonstrated by the presence of specific antibodies against HN in serum samples. No anti-viral treatments exist, but vaccines are available, although there are currently concerns over their efficacy.

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Keyword(s): APMV-1 , avian paramyxovirus , Newcastle disease virus and notifiable poultry disease
Funding
This study was supported by the:
  • department for environment, food and rural affairs (Award SV3002)
    • Principle Award Recipient: AshleyCharles Banyard
  • department for environment, food and rural affairs (Award SE2214)
    • Principle Award Recipient: CraigS Ross
  • department for environment, food and rural affairs (Award SV3400)
    • Principle Award Recipient: RowenaDE Hansen
© 2022 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
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2022-08-24
2024-05-09
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JMM Profile: Avian paramyxovirus type-1 and Newcastle disease: a highly infectious vaccine-preventable viral disease of poultry with low zoonotic potential
J. Med. Microbiol. 71, 001489 (2022); https://doi.org/10.1099/jmm.0.001489
/content/journal/jmm/10.1099/jmm.0.001489
/content/journal/jmm/10.1099/jmm.0.001489
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