1887

Abstract

-phosphoglucomutase, which converts glucose 6-phosphate to glucose 1-phosphate, is encoded by . The transcript is monocistronic and is initiated from a -like promoter. Mutants with a gene disruption in exhibited an altered cell wall muropeptide pattern and a lower teichoic acid content, and had reduced fitness both and . , the reduced fitness included reduced growth, reduced viability in the stationary phase and increased autolytic activity. , the -deficient strain had a lower virulence in a rat model of experimental endocarditis.

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2007-02-01
2023-02-06
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References

  1. Ames B. N. 1966; Assay of inorganic phosphate, total phosphate and phosphatases. Methods Enzymol 8:115–118
    [Google Scholar]
  2. Boels I. C., Ramos A., Kleerebezem M., de Vos W. M. 2001; Functional analysis of the Lactococcus lactis galU and galE genes and their impact on sugar nucleotide and exopolysaccharide biosynthesis. Appl Environ Microbiol 67:3033–3040 [CrossRef]
    [Google Scholar]
  3. Buchanan J. T., Stannard J. A., Lauth X., Ostland V. E., Powell H. C., Westerman M. E., Nizet V. 2005; Streptococcus iniae phosphoglucomutase is a virulence factor and a target for vaccine development. Infect Immun 73:6935–6944 [CrossRef]
    [Google Scholar]
  4. Chen J. D., Morrison D. A. 1988; Construction and properties of a new insertion vector, pJDC9, that is protected by transcriptional terminators and useful for cloning of DNA from Streptococcus pneumoniae . Gene 64:155–164 [CrossRef]
    [Google Scholar]
  5. Chen P. S., Toribara T. Y., Warner H. 1956; Microdetermination of phosphorus. Anal Chem 18:1756–1758
    [Google Scholar]
  6. Cisar J. O., Sandberg A. L., Reddy G. P., Abeygunawardana C., Bush C. A. 1997; Structural and antigenic types of cell wall polysaccharides from viridans group streptococci with receptors for oral actinomyces and streptococcal lectins. Infect Immun 65:5035–5041
    [Google Scholar]
  7. de Jonge B. L., Chang Y. S., Gage D., Tomasz A. 1992; Peptidoglycan composition of a highly methicillin-resistant Staphylococcus aureus strain. The role of penicillin binding protein 2A. J Biol Chem 267:11248–11254
    [Google Scholar]
  8. Douglas C. W., Heath J., Hampton K. K., Preston F. E. 1993; Identity of viridans streptococci isolated from cases of infective endocarditis. J Med Microbiol 39:179–182 [CrossRef]
    [Google Scholar]
  9. Entenza J. M., Caldelari I., Glauser M. P., Francioli P., Moreillon P. 1997; Importance of genotypic and phenotypic tolerance in the treatment of experimental endocarditis due to Streptococcus gordonii . J Infect Dis 175:70–76 [CrossRef]
    [Google Scholar]
  10. Hancock I. C., Baddiley J. 1985; Biosynthesis of the bacterial envelope polymers teichoic acid and teichuronic acid. In The Enzymes of Biological Membranes pp 279–307 Edited by Martonosi A. N. New York: Plenum;
    [Google Scholar]
  11. Hardy G. G., Caimano M. J., Yother J. 2000; Capsule biosynthesis and basic metabolism in Streptococcus pneumoniae are linked through the cellular phosphoglucomutase. J Bacteriol 182:1854–1863 [CrossRef]
    [Google Scholar]
  12. Hardy G. G., Magee A. D., Ventura C. L., Caimano M. J., Yother J. 2001; Essential role for cellular phosphoglucomutase in virulence of type 3 Streptococcus pneumoniae . Infect Immun 69:2309–2317 [CrossRef]
    [Google Scholar]
  13. Helmann J. D. 1995; Compilation and analysis of Bacillus subtilis σ A-dependent promoter sequences: evidence for extended contact between RNA polymerase and upstream promoter DNA. Nucleic Acids Res 23:2351–2360 [CrossRef]
    [Google Scholar]
  14. Heraief E., Glauser M. P., Freedman L. R. 1982; Natural history of aortic valve endocarditis in rats. Infect Immun 37:127–131
    [Google Scholar]
  15. Horne D. S., Tomasz A. 1993; Possible role of a choline-containing teichoic acid in the maintenance of normal cell shape and physiology in Streptococcus oralis . J Bacteriol 175:1717–1722
    [Google Scholar]
  16. Jorasch P., Wolter F. P., Zahringer U., Heinz E. 1998; A UDP glucosyltransferase from Bacillus subtilis successively transfers up to four glucose residues to 1,2-diacylglycerol: expression of ypfP in Escherichia coli and structural analysis of its reaction products. Mol Microbiol 29:419–430 [CrossRef]
    [Google Scholar]
  17. Kotloff K. L., Wasserman S. S., Jones K. F., Livio S., Hruby D. E., Franke C. A., Fischetti V. A. 2005; Clinical and microbiological responses of volunteers to combined intranasal and oral inoculation with a Streptococcus gordonii carrier strain intended for future use as a group A streptococcus vaccine. Infect Immun 73:2360–2366 [CrossRef]
    [Google Scholar]
  18. Lazarevic V., Soldo B., Medico N., Pooley H., Bron S., Karamata D. 2005; Bacillus subtilis α -phosphoglucomutase is required for normal cell morphology and biofilm formation. Appl Environ Microbiol 71:39–45 [CrossRef]
    [Google Scholar]
  19. Neuhaus F. C., Baddiley J. 2003; A continuum of anionic charge: structures and functions of d-alanyl-teichoic acids in Gram-positive bacteria. Microbiol Mol Biol Rev 67:686–723 [CrossRef]
    [Google Scholar]
  20. Pozzi G., Musmanno R. A., Lievens P. M., Oggioni M. R., Plevani P., Manganelli R. 1990; Method and parameters for genetic transformation of Streptococcus sanguis Challis. Res Microbiol 141:659–670 [CrossRef]
    [Google Scholar]
  21. Pozzi G., Contorni M., Oggioni M. R., Manganelli R., Tommasino M., Cavalieri F., Fischetti V. A. 1992; Delivery and expression of a heterologous antigen on the surface of streptococci. Infect Immun 60:1902–1907
    [Google Scholar]
  22. Rose R. K., Matthews S. P., Hall R. C. 1997; Investigation of calcium-binding sites on the surfaces of selected Gram-positive oral organisms. Arch Oral Biol 42:595–599 [CrossRef]
    [Google Scholar]
  23. Sabelnikov A. G., Greenberg B., Lacks S. A. 1995; An extended −10 promoter alone directs transcription of the Dpn II operon of Streptococcus pneumoniae . J Mol Biol 250:144–155 [CrossRef]
    [Google Scholar]
  24. Soldo B., Lazarevic V., Pooley H. M., Karamata D. 2002; Characterization of a Bacillus subtilis thermosensitive teichoic acid-deficient mutant: gene mnaA ( yvyH ) encodes the UDP- N -acetylglucosamine 2-epimerase. J Bacteriol 184:4316–4320 [CrossRef]
    [Google Scholar]
  25. Stutzmann Meier P., Entenza J. M., Vaudaux P., Francioli P., Glauser M. P., Moreillon P. 2001; Study of Staphylococcus aureus pathogenic genes by transfer and expression in the less virulent organism Streptococcus gordonii . Infect Immun 69:657–664 [CrossRef]
    [Google Scholar]
  26. Xu N., Huang Z. H., Gage D. A., de Jonge B. L. 1997; Structural characterization of peptidoglycan muropeptides by matrix-assisted laser desorption ionization mass spectrometry and postsource decay analysis. Anal Biochem 248:7–14 [CrossRef]
    [Google Scholar]
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