1887

Abstract

Excretion of organic acids, e.g. citrate, by anamorphic fungi is a frequent phenomenon in natural habitats and in laboratory cultures. In biotechnological processes for citrate production with extracellular citrate concentrations up to 1 mol l are achieved. Intracellular citrate concentrations are in the millimolar range. Therefore the question arises whether citrate excretion depends on active transport. In this article thermodynamic calculations are presented for citrate excretion by at an extracellular pH of 3 and by at an extracellular pH of 7. From the results of these calculations it is concluded that in both cases a passive transport step suffices for citrate excretion.

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2006-03-01
2020-08-08
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