1887

Abstract

Evidence is presented that expression of the gene, whose product is required for the correct assembly of the spore coat, is negatively controlled by the transcriptional regulator GerE. Mutations in the GerE-box, present in the promoter region, increased expression of this gene, which also remained elevated during late stages of sporulation, when in wild-type cells is normally turned off. Such alterations of expression did not significantly affect spore coat structure or function but caused the accumulation of CotC molecules in the mother cell compartment, most likely as a consequence of CotH-mediated protection of CotC.

Keyword(s): DMS, dimethyl sulfate
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2004-10-01
2024-03-28
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