1887

Abstract

is a beneficial legume symbiont, closely related to species, which are chronic mammalian pathogens. We discovered that the MsbA2 protein is essential to ensure the symbiotic interaction with the host plant, alfalfa. invades plant cells via plant-derived structures known as infection threads. However, in the absence of MsbA2, remains trapped within abnormally thickened infection threads and induces a heightened plant defence response, characterized by a substantial thickening of the nodule endodermis layer and the accumulation of polyphenolic compounds. The MsbA2 protein is homologous to the lipopolysaccharide/phospholipid trafficking protein MsbA. However, MsbA2 was not essential for the membrane transport of either lipopolysaccharide or phospholipids in . We determined that the gene is transcribed in free-living and that in the absence of MsbA2 the polysaccharide content of is altered. Consequently, we propose a model whereby the altered polysaccharide content of the mutant could be responsible for its symbiotic defect by inducing an inappropriate host response.

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2008-04-01
2020-08-07
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