1887

Abstract

The expression of the genes involved in the anaerobic degradation of benzoate in sp. CIB is controlled by the specific BzdR transcriptional repressor at the promoter. This catabolic promoter is also subject to catabolite repression by some organic acids. and experiments have shown that BzdR behaves as a repressor of the promoter by overlapping the transcription initiation site as well as the −35 and −10 boxes, benzoyl-CoA being the inducer molecule. In addition, by using a  : :  fusion both in sp. CIB and in an isogenic strain lacking the gene, we have shown that the succinate-dependent catabolite repression requires participation of the BzdR repressor.

Keyword(s): RNAP, RNA polymerase
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2008-01-01
2024-03-28
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