1887

Abstract

A virulent phage (CR1) capable of generalized transduction in was isolated from the environment and characterized. is a natural pathogen of mice, causing transmissible murine colonic hyperplasia. Sequencing of its genome has recently been completed and will soon be fully annotated and published. is an important model organism for infections caused by the human pathogens enteropathogenic and enterohaemorrhagic (EPEC and EHEC). CR1 uses a lipopolysaccharide receptor, has a genome size of approximately 300 kb, and is able to transduce a variety of markers. CR1 is the first reported transducing phage for and will be a useful tool for functional genomic analysis of this important natural murine pathogen.

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2007-09-01
2020-09-20
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