1887

Abstract

We have referenced and described transposable elements encoding DDE transposases. These elements belonged to nine families of insertion sequences (ISs) and to a family of conjugative transposons (Tn). An overview of the physiological impact of the insertion of all these elements is provided. DDE-transposable elements affect in a number of aspects of its capability to adapt to various environments and modulate the expression of several virulence genes, the genomic region and the genes involved in capsule expression and haemolysin transport being the targets of several different mobile elements. The referenced mobile elements modify behaviour by transferring new gene(s) to its genome, by modifying the expression of neighbouring genes at the integration site or by promoting genomic rearrangements. Transposition of some of these elements occurs , suggesting that by dynamically regulating some adaptation and/or virulence genes, they improve the ability of to reach different niches within its host and ensure the ‘success’ of the infectious process.

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2014-07-01
2024-12-12
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