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Volume 160, Issue 1

Lead resistance in micro-organisms Free

Abstract

Lead (Pb) is an element present in the environment that negatively affects all living organisms. To diminish its high toxicity, micro-organisms have developed several mechanisms that allow them to survive exposure to Pb(II). The main mechanisms of lead resistance involve adsorption by extracellular polysaccharides, cell exclusion, sequestration as insoluble phosphates, and ion efflux to the cell exterior. This review describes the various lead resistance mechanisms, and the regulation of their expression by lead binding regulatory proteins. Special attention is given to the Pbr system from CH34, which involves a unique mechanism combining efflux and lead precipitation.

  • Published Online:
Funding
This study was supported by the:
  • Ministry of Polish Science and Higher Education (Award N N305 185937)
  • UPGOW project task 55 at the University of Silesia within the European Social Fund
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2014-01-01
2024-04-23
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Lead resistance in micro-organisms
Microbiology 160, 12 (2014); https://doi.org/10.1099/mic.0.070284-0
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