@article{mbs:/content/journal/micro/10.1099/mic.0.041715-0, author = "Steyaert, Johanna M. and Weld, Richard J. and Mendoza-Mendoza, Artemio and Stewart, Alison", title = "Reproduction without sex: conidiation in the filamentous fungus Trichoderma", journal= "Microbiology", year = "2010", volume = "156", number = "10", pages = "2887-2900", doi = "https://doi.org/10.1099/mic.0.041715-0", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.041715-0", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = " Trichoderma spp. have served as models for asexual reproduction in filamentous fungi for over 50 years. Physical stimuli, such as light exposure and mechanical injury to the mycelium, trigger conidiation; however, conidiogenesis itself is a holistic response determined by the cell's metabolic state, as influenced by the environment and endogenous biological rhythms. Key environmental parameters are the carbon and nitrogen status and the C : N ratio, the ambient pH and the level of calcium ions. Recent advances in our understanding of the molecular biology of this fungus have revealed a conserved mechanism of environmental perception through the White Collar orthologues BLR-1 and BLR-2. Also implicated in the molecular regulation are the PacC pathways and the conidial regulator VELVET. Signal transduction cascades which link environmental signals to physiological outputs have also been revealed.", }