1887

Abstract

is a recently described novel endophytic fungus of (wild pineapple) growing in the Bolivian Amazon Basin. The fungus produces a mixture of volatile organic compounds (VOCs); some of the major components of this mixture, as determined by GC/MS, are propanoic acid, 2-methyl-, methyl ester; propanoic acid, 2-methyl-; 1-butanol, 3-methyl-;1-butanol, 3-methyl-, acetate; propanoic acid, 2-methyl-, 2-methylbutyl ester; and ethanol. The fungus does not, however, produce naphthalene or azulene derivatives as has been observed with many other members of the genus . The mixture of VOCs produced by cultures possesses antibiotic properties, as does an artificial mixture of a majority of the components. The VOCs of the fungus are effective against a wide range of plant pathogens, including the fungi , , and (the black sigatoka pathogen of bananas), and the serious bacterial pathogen of citrus, pv In addition, the VOCs of killed several human pathogens, including , and . Artificial mixtures of the fungal VOCs were both inhibitory and lethal to a number of human and plant pathogens, including three drug-resistant strains of The gaseous products of potentially could prove to be beneficial in the fields of medicine, agriculture, and industry.

Loading

Article metrics loading...

/content/journal/micro/10.1099/mic.0.032540-0
2010-01-01
2019-11-14
Loading full text...

Full text loading...

/deliver/fulltext/micro/156/1/270.html?itemId=/content/journal/micro/10.1099/mic.0.032540-0&mimeType=html&fmt=ahah

References

  1. Atmosukarto, I., Castillo, U., Hess, W. M., Sears, J. & Strobel, G. ( 2005; ). Isolation and characterization of Muscodor albus I-41.3s, a volatile antibiotic producing fungus. Plant Sci 169, 854–861.[CrossRef]
    [Google Scholar]
  2. Bacon, C. W. & White, J. F. ( 2000; ). Microbial Endophytes. New York: Marcel Dekker.
  3. Bull, A. T. ( 2004; ). Microbial Diversity and Bioprospecting. Washington, DC: American Society for Microbiology.
  4. Demain, A. L. ( 1981; ). Industrial microbiology. Science 214, 987–995.[CrossRef]
    [Google Scholar]
  5. Ezra, D. & Strobel, G. A. ( 2003; ). Effect of substrate on the bioactivity of volatile antimicrobials emitted by Muscodor albus. Plant Sci 165, 1229–1238.[CrossRef]
    [Google Scholar]
  6. Ezra, D., Hess, W. M. & Strobel, G. A. ( 2004; ). New endophytic isolates of Muscodor albus, a volatile-antibiotic-producing fungus. Microbiology 150, 4023–4031.[CrossRef]
    [Google Scholar]
  7. McAfee, B. J. & Taylor, A. ( 1999; ). A review of the volatile metabolites of fungi found on wood substrates. Nat Toxins 7, 283–303.[CrossRef]
    [Google Scholar]
  8. Mitchell, A. M., Strobel, G. A., Hess, W. M., Vargas, P. N. & Ezra, D. ( 2008; ). A record of Muscodor crispans, a novel endophyte from Ananas ananassoides in the Bolivian Amazon. Fungal Divers 31, 37–43.
    [Google Scholar]
  9. Mittermeier, R. A., Meyers, N., Gil, P. R. & Mittermeier, C. G. ( 1999; ). Hotspots: Earth's Biologically Richest and Most Endangered Ecoregions. Japan: Toppan Printing Co.
  10. Smith, S. A., Tank, D. C., Boulanger, L. A., Bascom-Slack, C. A., Eisenman, K., Babbs, B., Fenn, K., Greene, J. S., Hann, B. D. & other authors ( 2008; ). Bioactive endophytes support intensified exploration and conservation. PLoS One 3, e3052 [CrossRef]
    [Google Scholar]
  11. Strobel, G. A. ( 2006; ). Harnessing endophytes for industrial microbiology. Curr Opin Microbiol 9, 240–244.[CrossRef]
    [Google Scholar]
  12. Strobel, G. A. & Daisy, B. ( 2003; ). Bioprospecting for microbial endophytes and their natural products. Microbiol Mol Biol Rev 67, 491–502.[CrossRef]
    [Google Scholar]
  13. Strobel, G. A., Dirske, E., Sears, J. & Markworth, C. ( 2001; ). Volatile antimicrobials from Muscodor albus, a novel endophytic fungus. Microbiology 147, 2943–2950.
    [Google Scholar]
  14. Trun, N. J. & Gottesman, S. ( 1990; ). On the bacterial cell cycle: E.coli mutants with altered ploidy. Genes Dev 4, 2036–2047.[CrossRef]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/mic.0.032540-0
Loading
/content/journal/micro/10.1099/mic.0.032540-0
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error