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Volume 168, Issue 4

Symbiont-mediated immune priming in animals through an evolutionary lens Open Access

Abstract

Protective symbionts can defend hosts from parasites through several mechanisms, from direct interference to modulating host immunity, with subsequent effects on host and parasite fitness. While research on symbiont-mediated immune priming (SMIP) has focused on ecological impacts and agriculturally important organisms, the evolutionary implications of SMIP are less clear. Here, we review recent advances made in elucidating the ecological and molecular mechanisms by which SMIP occurs. We draw on current works to discuss the potential for this phenomenon to drive host, parasite, and symbiont evolution. We also suggest approaches that can be used to address questions regarding the impact of immune priming on host-microbe dynamics and population structures. Finally, due to the transient nature of some symbionts involved in SMIP, we discuss what it means to be a protective symbiont from ecological and evolutionary perspectives and how such interactions can affect long-term persistence of the symbiosis.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): host-microbe evolution , immune priming , parasites and Symbiosis
Funding
This study was supported by the:
  • European Research Council (Award COEVOPRO 802242)
    • Principle Award Recipient: KaylaC. King
  • National Science Foundation (Award 1907076)
    • Principle Award Recipient: KimL Hoang
© 2022 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
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2022-04-20
2024-04-24
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Symbiont-mediated immune priming in animals through an evolutionary lens
Microbiology 168, 001181 (2022); https://doi.org/10.1099/mic.0.001181
/content/journal/micro/10.1099/mic.0.001181
/content/journal/micro/10.1099/mic.0.001181
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