1887

Abstract

is an environmentally-ubiquitous bacterium that uses unique adaptations to kill other bacteria. The best-characterized strain, HD100, has a multistage lifestyle, with both a free-living attack phase and an intraperiplasmic growth and division phase inside the prey cell. Advances in understanding the basic biology and regulation of predation processes are paving the way for future potential therapeutic and bioremediation applications of this unusual bacterium.

Funding
This study was supported by the:
  • Wellcome Trust (Award 209437/Z/17/Z)
    • Principle Award Recipient: AndrewL Lovering
  • Wellcome Trust (Award 209437/Z/17/Z)
    • Principle Award Recipient: RElizabeth Sockett
Loading

Article metrics loading...

/content/journal/micro/10.1099/mic.0.001043
2021-04-12
2021-05-12
Loading full text...

Full text loading...

/deliver/fulltext/micro/167/4/mic001043.html?itemId=/content/journal/micro/10.1099/mic.0.001043&mimeType=html&fmt=ahah

References

  1. Sockett RE. Predatory lifestyle of Bdellovibrio bacteriovorus . Annu Rev Microbiol 2009; 63:523–539 [CrossRef][PubMed]
    [Google Scholar]
  2. Rendulic S, Jagtap P, Rosinus A, Eppinger M, Baar C. A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a genomic perspective. Science 2004; 303:689–692 [CrossRef]
    [Google Scholar]
  3. Harding CJ, Huwiler SG, Somers H, Lambert C, Ray LJ et al. A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus . Nat Commun 2020; 11:4817
    [Google Scholar]
  4. Dharani S, Kim DH, Shanks RMQ, Doi Y, Kadouri DE. Susceptibility of colistin-resistant pathogens to predatory bacteria. Res Microbiol 2018; 169:52–55 [CrossRef]
    [Google Scholar]
  5. Willis AR, Moore C, Mazon-Moya M, Krokowski S, Lambert C et al. Injections of predatory bacteria work alongside host immune cells to treat Shigella infection in zebrafish larvae. Current Biology 2016; 26:3343–3351 [CrossRef]
    [Google Scholar]
  6. Lambert C, Cadby IT, Till R, Bui NK, Lerner TR et al. Ankyrin-mediated self-protection during cell invasion by the bacterial predator Bdellovibrio bacteriovorus . Nat Commun 2015; 6:8884 [CrossRef]
    [Google Scholar]
  7. Kuru E, Lambert C, Rittichier J, Till R, Ducret A et al. Fluorescent D-amino-acids reveal bi-cellular cell wall modifications important for Bdellovibrio bacteriovorus predation. Nat Microbiol 2017; 2:1648–1657 [CrossRef]
    [Google Scholar]
  8. Makowski Łukasz, Trojanowski D, Till R, Lambert C, Lowry R et al. Dynamics of Chromosome Replication and Its Relationship to Predatory Attack Lifestyles in Bdellovibrio bacteriovorus . Appl Environ Microbiol 2019; 85: [CrossRef]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/mic.0.001043
Loading

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error