The social amoeba is a versatile organism that is unusual in alternating between single-celled and multi-celled forms. It possesses highly-developed systems for cell motility and chemotaxis, phagocytosis, and developmental pattern formation. As a soil amoeba growing on microorganisms, it is exposed to many potential pathogens; it thus provides fruitful ways of investigating host-pathogen interactions and is emerging as an influential model for biomedical research.

This study was supported by the:
  • Medical Research Council (Award MR/P028284/1)
    • Principle Award Recipient: CatherinePears
  • National Centre for the Replacement, Refinement and Reduction of Animals in Research (Award CrackIt Solution)
    • Principle Award Recipient: CatherinePears
  • National Centre for the Replacement, Refinement and Reduction of Animals in Research (Award NC/M000834/1)
    • Principle Award Recipient: CatherinePears
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.

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