Skip to content
1887

Microbiology Society logo Microbiology

Volume 165, Issue 11

Microbe Profile: : the model hyperthermophilic archaeon Open Access

This article is part of the Microbe Profiles collection.

Abstract

is a hyperthermophilic that grows well under laboratory conditions and, being naturally competent for genetic transformation, it has become a widely studied experimental model species. With the genome sequence available since 2004, combining genetic, enzymological and structural biochemical approaches has revealed previously unknown and unanticipated features of archaeal molecular biology and metabolism. DNA polymerase is already commercialized and with the details of metabolism and hydrogenase available, generating H from biopolymers solubilized at high temperatures, most notably chitin, now seems a very attractive possibility as a renewable energy bioprocess.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): archaea , genetics , hyperthermophile and Thermococcus kodakarensis
© 2019 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Loading

Article metrics loading...

/content/journal/micro/10.1099/mic.0.000839
2019-11-01
2025-01-17
Loading full text...

Full text loading...

/deliver/fulltext/micro/165/11/1166.html?itemId=/content/journal/micro/10.1099/mic.0.000839&mimeType=html&fmt=ahah

References

  1. Gehring AM, Astling DP, Matsumi R, Burkhart BW, Kelman Z et al. Genome replication in Thermococcus kodakarensis independent of Cdc6 and an origin of replication. Front Microbiol 2084; 2017:8
     [Google Scholar]
  2. Atomi H, Fukui T, Kanai T, Morikawa M, Imanaka T. Description of Thermococcus kodakaraensis sp. nov., a well studied hyperthermophilic archaeon previously reported as Pyrococcus sp. KOD1. Archaea 2004; 1:263–267 [View Article]
     [Google Scholar]
  3. Sato T, Fukui T, Atomi H, Imanaka T. Targeted gene disruption by homologous recombination in the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1. J Bacteriol 2003; 185:210–220 [View Article]
     [Google Scholar]
  4. Aono R, Sato T, Imanaka T, Atomi H. A pentose bisphosphate pathway for nucleoside degradation in archaea. Nat Chem Biol 2015; 11:355–360 [View Article]
     [Google Scholar]
  5. Burkhart BW, Febvre HP, Santangelo TJ. Distinct physiological roles of the three ferredoxins encoded in the hyperthermophilic archaeon Thermococcus kodakarensis . MBio 2019; 10:e02807–02818 [View Article]
     [Google Scholar]
  6. Kwon S, Watanabe S, Nishitani Y, Kawashima T, Kanai T et al. Crystal structures of a [NiFe] hydrogenase large subunit HyhL in an immature state in complex with a Ni chaperone HypA. Proc Natl Acad Sci U S A 2018; 115:7045–7050 [View Article]
     [Google Scholar]
  7. Gao L, Imanaka T, Fujiwara S. A mutant chaperonin that is functional at lower temperatures enables hyperthermophilic archaea to grow under cold-stress conditions. J Bacteriol 2015; 197:2642–2652 [View Article]
     [Google Scholar]
  8. Aslam M, Horiuchi A, Simons JR, Jha S, Yamada M et al. Engineering of the hyperthermophilic archaeon Thermococcus kodakarensis for chitin-dependent hydrogen production. Appl Environ Microbiol 2017; 83:e00280–17 [View Article]
     [Google Scholar]
/content/journal/micro/10.1099/mic.0.000839
Loading

Most cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error