1887

Abstract

is a food-borne bacterial pathogen that is responsible for listeriosis, a disease characterized by occasional febrile gastroenteritis in immunocompetent individuals, abortions in pregnant women, meningitis in the newborn and fatal bacteraemia in immunocompromised individuals or the elderly. The ability of to produce disease is intimately associated with its potential to traverse several human barriers (including the intestinal, placental and blood/brain barriers), to promote its internalization within diverse populations of epithelial cells and to proliferate in the intra-ic environment while escaping host immune responses. is often regarded as a paradigm for intracellular parasitism.

  • This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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/content/journal/micro/10.1099/mic.0.000800
2019-07-01
2021-10-27
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References

  1. Glaser P, Frangeul L, Buchrieser C, Rusniok C, Amend A et al. Comparative genomics of Listeria species. Science 2001; 294:849–852 [View Article]
    [Google Scholar]
  2. Maury MM, Tsai YH, Charlier C, Touchon M, Chenal-Francisque V et al. Uncovering Listeria monocytogenes hypervirulence by harnessing its biodiversity. Nat Genet 2016; 48:308–313 [View Article]
    [Google Scholar]
  3. Tilney LG, Portnoy DA. Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes . J Cell Biol 1989; 109:1597–1608 [View Article]
    [Google Scholar]
  4. Lecuit M, Vandormael-Pournin S, Lefort J, Huerre M, Gounon P et al. A transgenic model for listeriosis: role of internalin in crossing the intestinal barrier. Science 2001; 292:1722–1725 [View Article]
    [Google Scholar]
  5. Radoshevich L, Cossart P. Listeria monocytogenes: towards a complete picture of its physiology and pathogenesis. Nat Rev Microbiol 2018; 16:32–46 [View Article]
    [Google Scholar]
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