1887

Microbiology

Volume 163, Issue 12

Multi-copy single-stranded DNA in Free

Abstract

Multi-copy single-stranded DNA (msDNA) is composed of covalently bound single-stranded DNA and RNA, and synthesized by retron-encoded reverse transcriptase. msDNA-synthesizing systems are thought to be a recent acquisition by because, to date, only seven types of msDNA, which differ markedly in their primary nucleotide sequences, have been found in a small subset of strains. The wide use of in molecular research means that it is important to understand more about these stable, covalently bound, single-stranded DNA or RNA compounds. The present review provides insights into the molecular biosynthesis, distribution and function of msDNA to raise awareness about these special molecules.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): Escherichia coli , multi-copy single-stranded DNA and retron
© 2017 The Authors
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2017-12-01
2021-10-22
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Multi-copy single-stranded DNA in Escherichia coli
Microbiology 163, 1735 (2017); https://doi.org/10.1099/mic.0.000563
/content/journal/micro/10.1099/mic.0.000563
/content/journal/micro/10.1099/mic.0.000563
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