RT Journal Article SR Electronic(1) A1 Miteva-Staleva, Jeni G. A1 Krumova, Ekaterina T. A1 Vassilev, Spassen V. A1 Angelova, Maria B.YR 2017 T1 Cold-stress response during the stationary-growth phase of Antarctic and temperate-climate Penicillium strains JF Microbiology, VO 163 IS 7 SP 1042 OP 1051 DO https://doi.org/10.1099/mic.0.000486 PB Microbiology Society, SN 1465-2080, AB Cold-induced oxidative stress during the aging of three Penicillium strains (two Antarctic and one from a temperate region) in stationary culture was documented and demonstrated a significant increase in the protein carbonyl content, the accumulation of glycogen and trehalose, and an increase in the activities of antioxidant enzymes (superoxide dismutase and catalase). The cell response to a temperature downshift depends on the degree of stress and the temperature characteristics of the strains. Our data give further support for the role of oxidative stress in the aging of fungi in stationary cultures. Comparing the present results for the stationary growth phase with our previous results for the exponential growth phase was informative concerning the relationship between the cold-stress response and age-related changes in the tested strains. Unlike the young cells, stationary-phase cultures demonstrated a more pronounced level of oxidative damage, as well as decreased antioxidant defence., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.000486