1887

Abstract

At the end of June, over 120 microbiologists from 18 countries gathered in Dundee, Scotland for the fourth edition of the Young Microbiologists Symposium on ‘Microbe Signalling, Organisation and Pathogenesis’. The aim of the symposium was to give early career microbiologists the opportunity to present their work in a convivial environment and to interact with senior world-renowned scientists in exciting fields of microbiology research. The meeting was supported by the Microbiology Society, the Society of Applied Microbiology and the American Society for Microbiology with further sponsorship from the European Molecular Biology Organisation and the Royal Society of Edinburgh. In this report, we highlight some themes that emerged from the many interesting talks and poster presentations, as well as some of the other activities that were on offer at this energetic meeting.

Loading

Article metrics loading...

/content/journal/micro/10.1099/mic.0.000401
2017-02-06
2019-10-20
Loading full text...

Full text loading...

/deliver/fulltext/micro/163/1/4.html?itemId=/content/journal/micro/10.1099/mic.0.000401&mimeType=html&fmt=ahah

References

  1. Lee C, Wigren E, Trček J, Peters V, Kim J et al. A novel protein quality control mechanism contributes to heat shock resistance of worldwide-distributed Pseudomonas aeruginosa clone C strains. Environ Microbiol 2015;17:4511–4526 [CrossRef][PubMed]
    [Google Scholar]
  2. Ahmad I, Wigren E, Le Guyon S, Vekkeli S, Blanka A et al. The EAL-like protein STM1697 regulates virulence phenotypes, motility and biofilm formation in Salmonella typhimurium. Mol Microbiol 2013;90:1216–1232 [CrossRef][PubMed]
    [Google Scholar]
  3. Le Guyon S, Simm R, Rehn M, Römling U. Dissecting the cyclic di-guanylate monophosphate signalling network regulating motility in Salmonella enterica serovar Typhimurium. Environ Microbiol 2015;17:1310–1320 [CrossRef][PubMed]
    [Google Scholar]
  4. Ryan RP, Mccarthy Y, Andrade M, Farah CS, Armitage JP et al. Cell–cell signal-dependent dynamic interactions between HD-GYP and GGDEF domain proteins mediate virulence in Xanthomonas campestris. Proc Natl Acad Sci USA 2010;107:5989–5994 [CrossRef][PubMed]
    [Google Scholar]
  5. Bellini D, Caly DL, Mccarthy Y, Bumann M, An SQ et al. Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre. Mol Microbiol 2014;91:26–38 [CrossRef][PubMed]
    [Google Scholar]
  6. Corrigan RM, Abbott JC, Burhenne H, Kaever V, Gründling A. c-di-AMP is a new second messenger in Staphylococcus aureus with a role in controlling cell size and envelope stress. PLoS Pathog 2011;7:e1002217 [CrossRef][PubMed]
    [Google Scholar]
  7. Stano P, Rampioni G, Carrara P, Damiano L, Leoni L et al. Semi-synthetic minimal cells as a tool for biochemical ICT. Biosystems 2012;109:24–34 [CrossRef][PubMed]
    [Google Scholar]
  8. Ramsey MM, Whiteley M. Polymicrobial interactions stimulate resistance to host innate immunity through metabolite perception. Proc Natl Acad Sci USA 2009;106:1578–1583 [CrossRef][PubMed]
    [Google Scholar]
  9. Turner KH, Wessel AK, Palmer GC, Murray JL, Whiteley M. Essential genome of Pseudomonas aeruginosa in cystic fibrosis sputum. Proc Natl Acad Sci USA 2015;112:4110–4115 [CrossRef][PubMed]
    [Google Scholar]
  10. Stacy A, Mcnally L, Darch SE, Brown SP, Whiteley M. The biogeography of polymicrobial infection. Nat Rev Microbiol 2016;14:93–105 [CrossRef][PubMed]
    [Google Scholar]
  11. Gawthorne JA, Audry L, Mcquitty C, Dean P, Christie JM et al. Visualizing the translocation and localization of bacterial type III effector proteins by using a genetically encoded reporter system. Appl Environ Microbiol 2016;82:2700–2708 [CrossRef][PubMed]
    [Google Scholar]
  12. Paino A, Lohermaa E, Sormunen R, Tuominen H, Korhonen J et al. Interleukin-1β is internalised by viable Aggregatibacter actinomycetemcomitans biofilm and locates to the outer edges of nucleoids. Cytokine 2012;60:565–574 [CrossRef][PubMed]
    [Google Scholar]
  13. Ahlstrand T, Tuominen H, Beklen A, Torittu A, Oscarsson J et al. A novel intrinsically disordered outer membrane lipoprotein of Aggregatibacter actinomycetemcomitans binds various cytokines and plays a role in biofilm response to interleukin-1β and interleukin-8. Virulence doi:10.1080/21505594.2016.1216294 [Epub ahead of print] [CrossRef][PubMed]
    [Google Scholar]
  14. Paino A, Ahlstrand T, Nuutila J, Navickaite I, Lahti M et al. Identification of a novel bacterial outer membrane interleukin-1β-binding protein from Aggregatibacter actinomycetemcomitans. PLoS One 2013;8:e70509 [CrossRef][PubMed]
    [Google Scholar]
  15. Connolly JP, Goldstone RJ, Burgess K, Cogdell RJ, Beatson SA et al. The host metabolite D-serine contributes to bacterial niche specificity through gene selection. ISME J 2015;9:1039–1051 [CrossRef][PubMed]
    [Google Scholar]
  16. Connolly JP, Gabrielsen M, Goldstone RJ, Grinter R, Wang D et al. A highly conserved bacterial D-serine uptake system links host metabolism and virulence. PLoS Pathog 2016;12:e1005359 [CrossRef][PubMed]
    [Google Scholar]
  17. Krachler AM, Ham H, Orth K. Outer membrane adhesion factor multivalent adhesion molecule 7 initiates host cell binding during infection by Gram-negative pathogens. Proc Natl Acad Sci USA 2011;108:11614–11619 [CrossRef][PubMed]
    [Google Scholar]
  18. Planamente S, Salih O, Manoli E, Albesa‐jové D, Freemont PS et al. TssA forms a gp6‐like ring attached to the type VI secretion sheath. EMBO J 2016;28:e201694024
    [Google Scholar]
  19. Mars RA, Nicolas P, Ciccolini M, Reilman E, Reder A et al. Small regulatory RNA-induced growth rate heterogeneity of Bacillus subtilis. PLoS Genet 2015;11:e1005046 [CrossRef][PubMed]
    [Google Scholar]
  20. Cianfanelli FR, Alcoforado Diniz J, Guo M, de Cesare V, Trost M et al. VgrG and PAAR proteins define distinct versions of a functional type VI secretion system. PLoS Pathog 2016;12:e1005735 [CrossRef][PubMed]
    [Google Scholar]
  21. Barnwal RP, Loh E, Godin KS, Yip J, Lavender H et al. Structure and mechanism of a molecular rheostat, an RNA thermometer that modulates immune evasion by Neisseria meningitidis. Nucleic Acids Res 2016;44:9426–9437 [CrossRef][PubMed]
    [Google Scholar]
  22. Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK et al. Fucose sensing regulates bacterial intestinal colonization. Nature 2012;492:113–117 [CrossRef][PubMed]
    [Google Scholar]
  23. Kirkpatrick CL, Martins D, Redder P, Frandi A, Mignolet J et al. Growth control switch by a DNA-damage-inducible toxin–antitoxin system in Caulobacter crescentus. Nat Microbiol 2016;1:16008 [CrossRef][PubMed]
    [Google Scholar]
  24. Caly DL, Coulthurst SJ, Geoghegan JA, Malone JG, Ryan RP. Socializing, networking and development: a report from the second 'Young Microbiologists Symposium on Microbe Signalling, Organisation and Pathogenesis'. Mol Microbiol 2012;86:501–512 [CrossRef][PubMed]
    [Google Scholar]
  25. Caly DL, Coulthurst SJ, An SQ, Helaine S, Malone JG et al. Communication, cooperation, and social interactions: a report from the third Young Microbiologists Symposium on Microbe Signalling, Organisation, and Pathogenesis. J Bacteriol 2014;196:3527–3533 [CrossRef][PubMed]
    [Google Scholar]
  26. Ryan RP, Romeo T, de Keersmaecker SC, Coulthurst SJ. Nurturing scientific mutualism: a report from the 'Young Microbiologists Mini-Symposium on Microbe Signalling, Organisation and Pathogenesis'. Mol Microbiol 2009;73:760–774 [CrossRef][PubMed]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/mic.0.000401
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error