Ten strains isolated from four patients and responsible for bone infections following implantation of orthopaedic material were compared to four strains collected from milk samples of healthy goats. The following characteristics were investigated: SmaI patterns, hybridization patterns with pBA2 (ribotypes), slime production, adhesion to matrix proteins (fibrinogen, fibronectin, collagen) and the staphylococcal adhesion genes (). None of the characteristics enabled us to distinguish the human strains from the goat strains. Slime was occasionally produced by strains but all of them carried nucleotide sequences hybridizing at low stringency with the following genes: encoding a autolysin binding vitronectin and responsible for the primary adhesion to polystyrene, ica operon involved in the biosynthesis of a extracellular polysaccharide, and the part of encoding the serine-aspartate repeated region of a cell-wall fibrinogen-binding protein.


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