1887

Abstract

Summary: Southern blotting, sequence analysis and PCR experiments showed that and BCG lack a 12·7 kb fragment present in the genome of This region is 337 bp downstream of the RD2 region, which was previously described as being absent from some BCG strains. The 12·7 kb fragment should be useful as a target for a PCR test to differentiate and An analysis of the 12·7 kb region suggests that it represents a deletion in rather than an insertion in The deletion removes most of the operon, one of four highly related operons which may be involved in cell entry, and therefore it may contribute to differences in virulence or host range in the two species.

Loading

Article metrics loading...

/content/journal/micro/10.1099/13500872-145-4-893
1999-04-01
2019-10-15
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/micro/10.1099/13500872-145-4-893
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error