1887

Abstract

Two mutants of (classical and El Tor biotypes) were constructed by disruption of the wild-type gene with mutated sequences of cloned in the suicide vector pGP704. Mutants defective in the gene were compared with their respective parent strains with regard to their adherence to isolated rabbit intestine and colonization of intestine of infant mice. The mutation in was found to diminish adherence and markedly affected colonization.

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1994-05-01
2022-01-25
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