1887

Abstract

We examined endogenous ADP-ribosylation of proteins during the development of the prokaryote and endogenous ADP-ribosylation of proteins was detected and the profile of modified proteins changed during development. Adenosine and nicotinamide inhibited ADP-ribosylation. Nicotinamide stimulated cells at low density to develop, in a manner similar to that previously observed with adenosine. Higher concentrations of nicotinamide inhibited aggregation. The effects of nicotinamide on developing cells correlate with its effects on ADP-ribosylation and the developmental profile of putative ADP-ribosylation substrates. These results suggest that ADP-ribosylation may regulate developmental proteins in

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/content/journal/micro/10.1099/13500872-140-11-3167
1994-11-01
2019-10-15
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http://instance.metastore.ingenta.com/content/journal/micro/10.1099/13500872-140-11-3167
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