SUMMARY: accumulated Co and Cd by two processes: the first, which was metabolism-independent, was presumably cation binding to the cell surface; this was followed by metabolism-dependent, progressive uptake of relatively large amounts of the cations. Two K ions were released for each Co ion taken up in freshly prepared cell suspensions whereas extensive loss of cell K followed the uptake of Cd. Co and Cd appeared to be accumulated via a general cation uptake system, with limited specificity related to the ionic radii of the cations.


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