1887

Abstract

Summary: Diploid strains of grown on medium supplemented with griseofulvin (20 μg ml) produced fast-growing sectors of two types after 7 to 28 days incubation: these were diploid somatic recombinants and haploids. A dikaryon grown on the same medium broke down to give one haploid component only; resolution of this dikaryon and a near-isogenic diploid resulted in selection for sectors carrying a gene for resistance to griseofulvin. The use of this antibiotic is suggested as a tool for routine haploidization in

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/content/journal/micro/10.1099/00221287-98-2-529
1977-02-01
2021-10-15
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