%0 Journal Article %A Takeo, K. %A Shigeta, Michiko %A Takagi, Y. %T Plasma Membrane Ultrastructural Differences Between the Exponential and Stationary Phases of Saccharomyces cerevisiae as Revealed by Freeze-Etching %D 1976 %J Microbiology, %V 97 %N 2 %P 323-329 %@ 1465-2080 %R https://doi.org/10.1099/00221287-97-2-323 %I Microbiology Society, %X Summary: Ultrastructural changes in the plasma membrane of Saccharomyces cerevisiae during the exponential and stationary growth phases were studied by freeze-etching. In the exponential phase, plasma membrane-intercalated particles were distributed randomly. In the stationary phase, several areas of the plasma membrane showed a hexagonal arrangement of particles; these areas appeared to increase with the age of the culture. The polarity of the particles also changed partially: the E-face of the plasma membrane was only sparsely embedded with particles in exponential phase cells, but relatively densely embedded in stationary phase cells. Invaginations of the plasma membrane on the P-face were devoid of particles during both growth phases. Invaginations of the E-face were sparsely embedded with particles in exponential phase cells, but densely embedded with particles in stationary phase cells. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-97-2-323