
Full text loading...
Summary: Escherichia coli k12 cannot grow on d-arabitol, l-arabitol, ribitol or xylitol ( Reiner, 1975 ). Using a mutant of E. coli K12 (strain 3; Sridhara et al., 1969 ) that can grow on l-1,2-propanediol, a second-stage mutant was isolated which can utilize d-arabitol as sole source of carbon and energy for growth. d-Arabitol is probably transported into the bacteria by the same system as that used for the transport of l-1,2-propanediol. The second-stage mutant constitutively synthesizes a new dehydrogenase, which is not present in the parent strain 3. This enzyme, whose native substrate may be d-galactose, apparently dehydrogenates d-arabitol to d-xylulose, and its structural gene is located at 68·5 ± 1 min on the E. coli genetic map. d-Xylulose is subsequently catabolized by the enzymes of the d-xylose metabolic pathway.
Article metrics loading...
Full text loading...
References
Data & Media loading...