1887

Abstract

Summary: The adenine nucleotide levels and derived energy charge value of a tyrothricin-producing strain of under aerobic conditions were in good agreement with published values for other bacteria. When growing cultures of underwent a transition from aerobic to anaerobic conditions, cyclic variations in the level of adenine nucleotides were observed and the energy charge value oscillated between 0·87 and 0·70. The significance of these changes is considered in relation to antibiotic production as a possible regulatory mechanism in energy metabolism. It is concluded that tyrothricin is not directly involved in the observed changes in energy charge value.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-94-1-68
1976-05-01
2022-01-21
Loading full text...

Full text loading...

/deliver/fulltext/micro/94/1/mic-94-1-68.html?itemId=/content/journal/micro/10.1099/00221287-94-1-68&mimeType=html&fmt=ahah

References

  1. Atkinson D. E. 1968; Citrate and the citrate cycle in the regulation of energy metabolism. In The Metabolic Roles of Citrate pp. 23–40 Goodwin T. W. Edited by London and New York: Academic Press;
    [Google Scholar]
  2. Bergmeyer H. H. 1962 Methods of Enzymatic Analysis p. 1005 London and New York: Academic Press;
    [Google Scholar]
  3. Chapman A. G., Fall L., Atkinson D. E. 1971; Adenylate energy charge in Escherichia coli during growth and starvation. Journal of Bacteriology 108:1072–1086
    [Google Scholar]
  4. Chin B., Bernstein I. A. 1968; ATP and synchronous mitosis in Physarum polycephalum.. Journal of Bacteriology 96:330–337
    [Google Scholar]
  5. Cole H. A., Wimpenny J. W. T., Hughes D. E. 1967; The ATP pool in E. coli. I. Measurement using a modified luciferase assay. Biochimica et biophysica acta 143:445–453
    [Google Scholar]
  6. Davison J. A., Fynn G. H. 1974; Interference by phosphates in ATP estimation by the luciferase method. Analytical Biochemistry 58:632–637
    [Google Scholar]
  7. Decker K., Pfizer S. 1972; Determination of steady slate concentrations of adenine nucleotides in growing Clostridium kluyveri cells by biosynthetic labelling. Analytical Biochemistry 50:529–539
    [Google Scholar]
  8. Dietzler D. N., Leckie M. P., Lais C. J. 1973; Rates of glycogen synthesis and the cellular levels of the ATP and FDP during exponential growth and the nitrogen limited stationary phase of E. coli W4597(K). Archives of Biochemistry and Biophysics 156:684–693
    [Google Scholar]
  9. Fynn G. H., Seddon B. 1971; Terminal oxidations in Bacillus brevis. III. Evidence of TCA cycle enzyme activity. Archiv für Mikrobiologie 79:274–279
    [Google Scholar]
  10. Fynn G. H., Thomas D. V., Seddon B. 1972; On the role of menaquinone in the reduced nicotinamide adenine dinucleotide oxidative pathway of Bacillus brevis.. Journal of General Microbiology 70:271–275
    [Google Scholar]
  11. Glazer V. M., Silaeva S. A., Shestakov S. V. 1966; The effect of gramicidin S on phosphorus metabolism in Bacillus brevis.. Biokhimiya 31:1135–1141
    [Google Scholar]
  12. Harrison D. E. F., Maitra P. K. 1969; Control of respiration and metabolism in growing Klebsiella aerogenes. The role of adenine nucleotides. Biochemical Journal 112:647–656
    [Google Scholar]
  13. Hunter F. E., Schwartz L. S. 1967 In Antibiotics 1 pp. 636–641 Gottlieb D., Shaw P. D. Edited by Berlin: Springer-Verlag;
    [Google Scholar]
  14. Knowles C. J., Smith L. 1970; Measurement of ATP levels of intact Azotobacter vinelandii under different conditions. Biochimica et biophysica acta 197:152–160
    [Google Scholar]
  15. Miovic M. L., Gibson J. 1973; Nucleotide pools and adenylate energy charge in balanced and unbalanced growth cf Chromatium.. Journal of Bacteriology 114:86–95
    [Google Scholar]
  16. Neubert D., Lehninger A. L. 1962; The effect of oligomycin, gramicidin and other antibiotics on reversal of mitochondrial swellings by adenosine triphosphate. Biochimica et biophysica acta 62:556–565
    [Google Scholar]
  17. Robertson A. M., Wolfe R. S. 1970; ATP pools in Methanobacterium.. Journal of Bacteriology 102:43–51
    [Google Scholar]
  18. Scherbaum O. H., Chou C. L., Saraydarian K. H., Byfield J. E. 1962; The effect of temperature shifts on the intracellular level of nucleoside triphosphates in Tetrahymena pyriformis.. Canadian Journal of Microbiology 8:753–760
    [Google Scholar]
  19. Seddon B., Fynn G. H. 1970; Terminal oxidations in Bacillus brevisatccioo68. I. Measurement of the NADH oxidase activity. Biochimica et biophysica acta 216:435–438
    [Google Scholar]
  20. Seddon B., Fynn G. H. 1971; Terminal oxidations in Bacillus brevis. II. The electron transport systems. Archiv für Mikrobiologie 77:252–261
    [Google Scholar]
  21. Seddon B., Fynn G. H. 1973; Energetics of growth in a tyrothricin-producing strain of Bacillus brevis.. Journal of General Microbiology 74:305–314
    [Google Scholar]
  22. Silaeva S. A., Glazer V. M., Shestakov S. V., Prokofiev M. A. 1965; Nucleotides of Bacillus brevisg.b. cells producing and not producing gramicidin S. Biokhimiya 30:947–955
    [Google Scholar]
  23. Slayman C. L. 1973; Adenine nucleotide levels in Neurospora as influenced by conditions of growth and by metabolic inhibitors. Journal of Bacteriology 114:752–766
    [Google Scholar]
  24. Strange R. E., Wade H. R., Dark F. A. 1963; The effect of starvation on the ATP concentration in Aerobacter aerogenes.. Nature; London: 19955–57
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-94-1-68
Loading
/content/journal/micro/10.1099/00221287-94-1-68
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error