RT Journal Article SR Electronic(1) A1 Shepherd, M. G. A1 Sullivan, P. A.YR 1976 T1 The Production and Growth Characteristics of Yeast and Mycelial Forms of Candida albicans in Continuous Culture JF Microbiology, VO 93 IS 2 SP 361 OP 370 DO https://doi.org/10.1099/00221287-93-2-361 PB Microbiology Society, SN 1465-2080, AB SUMMARY: The growth characteristics of Candida albicans cmi45,348 have been examined under aerobic conditions in continuous culture. At different steady states the environment was controlled with respect to the concentrations of dissolved oxygen, carbon and nitrogen, the pH, and the temperature. Dry matter, substrate concentration, yield, specific oxygen uptake, specific carbon dioxide release and respiration quotient were examined as a function of the dilution rate. The morphology depended on the carbon source. Maltose produced a mycelial morphology, whereas with lactate a yeast culture was obtained. With fructose or glucose as a carbon source a mixed morphology of yeast, pseudo-mycelial and mycelial forms was produced. A large number of different growth conditions were examined in batch culture but a mixed morphology was always obtained., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-93-2-361