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Abstract
SUMMARY: Under certain conditions chloramphenicol influences the growth and division of Bacterium coli so that abnormal forms are produced. These include long and sometimes pointed filaments and branched forms which seem to arise from organisms with abnormal growing points. Changes in morphology are preceded by changes in nuclear structure. The processes described occur only within critical limits of concentration of the antibiotic, and these limits vary when different strains of Bacterium coli are used.
- Received:
- Published Online:
© Society for General Microbiology, 1953