1887

Abstract

Summary: Strains of belonging to Types 5, 11,12, 27 and 44 share a minor T antigen. In addition, there are three major T antigens in this set of types, one in Type 11, one in Type 12 and the third common to Types 5, 27 and 44.

T antigen, prepared by Pakula’s method, is a satisfactory fraction for absorbing the antibodies from serum, the advantage being that very little serum is lost with each absorption because the volume of T antigen required is so small. The Pakula method of extraction of the T antigen can also be satisfactorily used in routine typing. Type 11 strains can be definitely identified by the T precipitin test, and this test can also be used for identifying Type 12 strains that give no reaction with Type 12 anti- sera. There are some strains which have agglutination patterns of the series 5, 11, 12, 27 and 44 but which give no precipitation with the T antisera. It may be that in these the major T antigen has not been recognized.

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/content/journal/micro/10.1099/00221287-9-1-110
1953-08-01
2021-07-29
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References

  1. Griffith F. 1934; The serological classification of Streptococcus pyogenes. . J. Hyg., Camb. 34:542
    [Google Scholar]
  2. Lancefield R. C. 1940–1; Specific relationship of cell composition to biological activity of hemolytic streptococci. Harvey Led. 36:251
    [Google Scholar]
  3. Pakula R. 1951; Extraction of the T antigen of Streptococcus pyogenes. . J. gen. Microbiol 5:640
    [Google Scholar]
  4. Stewart W.A., Lancefield R.C., Wilson A.T., Swift H.F. 1944; Studies on the antigenic composition of Group A hemolytic streptococci. IV.Related T but distinct M antigens in Types 15, 17, 19, 23, 30 and in Types 4, 24, 26, 28, 29, 46. Identification by slide agglutination. J. exp. Med. 79:99
    [Google Scholar]
  5. Swift H.F., Wilson A.T., Lancefield R.C. 1943; Typing Group A hemolytic streptococci by M precipitin reactions in capillary pipettes. J. exp. Med. 78:127
    [Google Scholar]
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