@article{mbs:/content/journal/micro/10.1099/00221287-88-2-355, author = "Sharpe, M. Elisabeth and Brock, J. H. and Phillips, B. A.", title = "Glycerol Teichoic Acid as an Antigenic Determinant in a Gram-negative Bacterium Butyrivibrio fibrisolvens", journal= "Microbiology", year = "1975", volume = "88", number = "2", pages = "355-363", doi = "https://doi.org/10.1099/00221287-88-2-355", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-88-2-355", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "SUMMARY: An antigenic determinant isolated from a strain of the Gram-negative bacterium Butyrivibrio fibrisolvens reacted with specific antisera to the polyglycero-phosphate backbone of membrane teichoic acids of lactobacilli. It gave a reaction of identity with membrane glycerol lipoteichoic acid and glycerol teichoic acid preparations from lactobacilli, and with phenol extracts of other Gram-positive bacteria. The antigen-antibody reaction was strongly inhibited by glycerol-phosphoryl-glycerol-phosphoryl-glycerol and the chemical composition was consistent with glycerol teichoic acid. It was concluded that this Gram-negative bacterium contained a glycerol teichoic acid whose polyglycerophosphate backbone was acting as antigenic determinant. Extracts of 33 out of 52 other strains of butyrivibrios examined gave similar reactions.", }