SUMMARY: Cytochalasin B inhibited the radial growth rate of Polyporus biennis, and caused an increase in hyphal density through a reduction in the distance between successive branches. Cytochalasin B also produced irregular hyphal profiles and, in a small percentage of hyphae, forked apices. The position of clamp connexions was little affected by cytochalasin B, but the developmental process was specifically inhibited during initiation and during the last two stages, when contact and dissolution of the clamp were occurring. There were no major disruptions of the ultrastructure of the dolipore/parenthesome septum caused by cytochalasin B treatment.
BetinaV.,
MičkováD.1973; Morphogenetic activity of cytochalasins, cyanein, and monorden in Botrytis cinerea. Zeitschrift für allgemeine Mikrobiologie 13:287–298
BetinaV.,
MičekováD.,
NemecP.1972; Antimicrobial properties of cytochalasins and their alteration of fungal morphology. Journal of General Microbiology 71:343–349
EstensenR. D.,
PlagemannP. G. W.1972; Cytochalasin B: inhibition of glucose and glucosamine transport. Proceedings of the National Academy of Sciences of the United States of America 69:1430–1434
RaudaskoskiM.1970; Occurrence of microtubules and microfilaments, and origin of septa in dikaryotic hyphae of Schizophyllum commune. Protoplasma 70:415–422