SUMMARY: In a sample of 52 wild-type isolates of penicillin titre ranged from 0.0 to 14.4 units/ml. These differences in titre were under genetic control. Most of the variation between isolates was attributable to differences between heterokaryon-compatibility groups although significant differences were also found within groups. Genetic variation for penicillin titre was observed among the progeny in four of seven crosses between wild-type isolates. In these four crosses the variation was continuous, indicating that this is a polygenically determined character, and progeny with titres superior and inferior to those of the parents were produced. The genes determining penicillin production are predominantly additive in their action. Crosses between heterokaryon-incompatible isolates generated more genetic variation than those involving compatible parents, supporting the hypothesis that heterokaryon-compatible isolates are frequently closely related.


Article metrics loading...

Loading full text...

Full text loading...


Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error