SUMMARY: The respiratory activity of the sugar-tolerant (osmophilic) yeast, and the non-tolerant species, , were compared after growth in a complex basal medium, the medium supplemented with polyethylene glycol (mol. wt 200) to give a water activity of 0.95, and the medium supplemented with glucose (24 and 36%, w/v). The properties compared were (glucose), NADH oxidase activity of isolated mitochondrial fractions, and cytochrome content. When grown in the basal medium was somewhat more active than by all criteria. Growth in the media supplemented were high glucose concentrations produced catabolite repression of respiration in but not in The implications of this difference for polyol biosynthesis and the water relations of the sugar-tolerant species are discussed.


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