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Summary: Rowson-Parr virus (RPV), which causes lymphoma in Balb/c mice and also depresses the splenic haemolytic plaque-forming cell response to sheep erythrocytes, greatly exacerbates infections caused by two murine Plasmodium species. One of these, Plasmodium vinckei chabaudi, infects mature erythrocytes and the other, Plasmodium berghei yoelii, infects mainly reticulocytes. Mice infected with RPV and either Plasmodium showed a similar degree of reticulocytosis to those which received the Plasmodium alone. Antiplasmodial antibody was much higher in mice which received Plasmodium alone than in those also infected with RPV.
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