%0 Journal Article %A Karst, F. %A Lacroute, F. %T Yeast Mutant Requiring an Organic Solvent for Growth %D 1974 %J Microbiology, %V 85 %N 1 %P 1-10 %@ 1465-2080 %R https://doi.org/10.1099/00221287-85-1-1 %I Microbiology Society, %X SUMMARY: A mutation has been found which makes yeast dependent on either organic solvents or high temperature for growth. This phenotype suggested an impairment in lipid mobility, but a chemical analysis has disproved this hypothesis. A study of the physiology of the mutant shows an impairment in RNA biosynthesis. This may be due either to a primary effect of the mutation or, more probably, to a secondary effect through regulation. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-85-1-1